Motif ID: MEF2{A,B,C,D}.p2

Z-value: 1.335


Transcription factors associated with MEF2{A,B,C,D}.p2:

Gene SymbolEntrez IDGene Name
MEF2A 4205 myocyte enhancer factor 2A
MEF2B 100271849 myocyte enhancer factor 2B
MEF2BNB-MEF2B 4207 MEF2BNB-MEF2B readthrough
MEF2C 4208 myocyte enhancer factor 2C
MEF2D 4209 myocyte enhancer factor 2D



Activity profile for motif MEF2{A,B,C,D}.p2.

activity profile for motif MEF2{A,B,C,D}.p2


Sorted Z-values histogram for motif MEF2{A,B,C,D}.p2

Sorted Z-values for motif MEF2{A,B,C,D}.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of MEF2{A,B,C,D}.p2

PNG image of the network

In order to view interactive SVG image please either update your browser to latest version or install SVG plugin.


View svg image
View png image


Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr7_-_96471544 1.648 DLX6-AS1
DLX6 antisense RNA 1 (non-protein coding)
chr5_-_16561936 1.448 NM_019000
FAM134B
family with sequence similarity 134, member B
chr1_-_116184846 1.371 NM_001111061
NHLH2
nescient helix loop helix 2
chr18_-_3209986 1.370 NM_003803
NM_019856
MYOM1

myomesin 1, 185kDa

chr3_+_50291521 1.314 NM_153215
C3orf45
chromosome 3 open reading frame 45
chr2_+_88148413 1.282 NM_198274
SMYD1
SET and MYND domain containing 1
chr12_-_43555607 1.156 NM_001145109
NELL2
NEL-like 2 (chicken)
chr10_+_111755715 1.084 NM_019903
ADD3
adducin 3 (gamma)
chr18_-_33399997 1.061 NM_001025087
NM_001025088
NM_001025089
NM_020180
CELF4



CUGBP, Elav-like family member 4



chr10_-_91395194 1.032 NM_148977
PANK1
pantothenate kinase 1
chrX_-_21686079 0.998 NM_014332
SMPX
small muscle protein, X-linked
chr10_-_69125932 0.973 NM_013266
CTNNA3
catenin (cadherin-associated protein), alpha 3
chr3_+_35658852 0.940 NM_016300
ARPP21
cAMP-regulated phosphoprotein, 21kDa
chr3_+_129117007 0.930 KBTBD12
kelch repeat and BTB (POZ) domain containing 12
chr1_-_116112684 0.910 CASQ2
calsequestrin 2 (cardiac muscle)
chr15_-_68781662 0.905 NM_001008224
UACA
uveal autoantigen with coiled-coil domains and ankyrin repeats
chr9_+_99303639 0.870 NM_003275
TMOD1
tropomodulin 1
chr9_+_5221401 0.866 NM_002195
INSL4
insulin-like 4 (placenta)
chr1_-_116112921 0.850 NM_001232
CASQ2
calsequestrin 2 (cardiac muscle)
chr14_+_61532293 0.842 NM_031914
SYT16
synaptotagmin XVI
chr3_-_148607096 0.841 NM_032153
ZIC4
Zic family member 4
chr18_-_3209846 0.821 MYOM1
myomesin 1, 185kDa
chr1_-_116112853 0.803 CASQ2
calsequestrin 2 (cardiac muscle)
chr11_-_19180092 0.788 NM_001127656
NM_003476
CSRP3

cysteine and glycine-rich protein 3 (cardiac LIM protein)

chr3_+_122794859 0.773 NM_016298
FBXO40
F-box protein 40
chr9_+_96806235 0.758 C9orf3
chromosome 9 open reading frame 3
chr12_-_55931172 0.751 NM_145064
STAC3
SH3 and cysteine rich domain 3
chr8_-_110730183 0.749 NM_001099747
NM_001099748
NM_001099749
NM_001099750
NM_017786
SYBU




syntabulin (syntaxin-interacting)




chr1_-_232681471 0.747 NM_005646
TARBP1
TAR (HIV-1) RNA binding protein 1
chr10_-_14412813 0.721 NM_018027
FRMD4A
FERM domain containing 4A
chr5_-_137502975 0.719 NM_003551
NME5
non-metastatic cells 5, protein expressed in (nucleoside-diphosphate kinase)
chr1_-_115039614 0.711 NM_000036
NM_001172626
AMPD1

adenosine monophosphate deaminase 1

chr11_-_123695302 0.700 NM_001002918
OR8D2
olfactory receptor, family 8, subfamily D, member 2
chr7_+_80069439 0.676 NM_001001547
CD36
CD36 molecule (thrombospondin receptor)
chr7_+_94953148 0.643 NM_016116
NM_145872
ASB4

ankyrin repeat and SOCS box containing 4

chr5_-_115938305 0.636 NM_020796
SEMA6A
sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6A
chr10_+_18729518 0.612 NM_201570
CACNB2
calcium channel, voltage-dependent, beta 2 subunit
chr13_-_50315832 0.612 NM_198989
DLEU7
deleted in lymphocytic leukemia, 7
chr11_-_18214891 0.607 NM_006512
SAA4
serum amyloid A4, constitutive
chr5_+_132433979 0.598 HSPA4
heat shock 70kDa protein 4
chr1_+_144124547 0.598 NM_145277
NM_202004
NM_213652
NM_213653
HFE2



hemochromatosis type 2 (juvenile)



chr10_-_7491204 0.596 NM_001018039
SFMBT2
Scm-like with four mbt domains 2
chr3_-_171070314 0.589 NM_024727
LRRC31
leucine rich repeat containing 31
chr7_-_113346284 0.586 NM_002711
PPP1R3A
protein phosphatase 1, regulatory (inhibitor) subunit 3A
chr6_+_127940011 0.583 NM_001010905
C6orf58
chromosome 6 open reading frame 58
chr11_-_31782169 0.581 PAX6
paired box 6
chr7_+_154943466 0.567 NM_001427
EN2
engrailed homeobox 2
chr2_-_165768798 0.567 NM_001081676
NM_001081677
NM_006922
SCN3A


sodium channel, voltage-gated, type III, alpha subunit


chr4_-_46690197 0.563 NM_000809
GABRA4
gamma-aminobutyric acid (GABA) A receptor, alpha 4
chr4_-_56153135 0.562 NM_152401
PDCL2
phosducin-like 2
chr7_+_93373755 0.558 NM_021955
GNGT1
guanine nucleotide binding protein (G protein), gamma transducing activity polypeptide 1
chr7_-_15692798 0.557 NM_005924
MEOX2
mesenchyme homeobox 2
chr5_+_127016605 0.556 NM_001127385
CTXN3
cortexin 3
chr5_-_94250357 0.552 MCTP1
multiple C2 domains, transmembrane 1
chr7_-_124217978 0.551 NM_001024603
LOC154872
hypothetical protein LOC154872
chr4_+_114190233 0.545 NM_001148
NM_020977
ANK2

ankyrin 2, neuronal

chr9_-_21218132 0.545 NM_021268
IFNA17
interferon, alpha 17
chr1_-_147665783 0.542 HIST2H2BF
histone cluster 2, H2bf
chr4_+_141484046 0.537 NM_001153446
NM_001153635
NM_001153585
NM_001153690
SCOC



short coiled-coil protein



chr6_-_26216299 0.536 NM_005323
HIST1H1T
histone cluster 1, H1t
chr7_-_83116414 0.531 NM_012431
SEMA3E
sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3E
chr3_-_109730858 0.517 NM_014981
MYH15
myosin, heavy chain 15
chr19_+_17923110 0.512 NM_002248
KCNN1
potassium intermediate/small conductance calcium-activated channel, subfamily N, member 1
chr16_-_70591377 0.496 NM_181536
PKD1L3
polycystic kidney disease 1-like 3
chr3_+_129124591 0.496 NM_207335
KBTBD12
kelch repeat and BTB (POZ) domain containing 12
chr9_+_5880801 0.496 NM_005511
MLANA
melan-A
chr3_+_187840842 0.494 NM_014375
FETUB
fetuin B
chr4_-_122521562 0.492 NM_198179
QRFPR
pyroglutamylated RFamide peptide receptor
chr7_-_27133163 0.492 NM_153631
HOXA3
homeobox A3
chr17_+_7495436 0.483 ATP1B2
ATPase, Na+/K+ transporting, beta 2 polypeptide
chr1_-_150328153 0.481 NM_001008536
TCHHL1
trichohyalin-like 1
chr2_-_27469947 0.481 FTH1P3
ferritin, heavy polypeptide 1 pseudogene 3
chr2_-_73350103 0.479 NM_001080410
FBXO41
F-box protein 41
chr2_-_20390601 0.475 NM_015317
PUM2
pumilio homolog 2 (Drosophila)
chr1_+_40508336 0.470 ZMPSTE24
zinc metallopeptidase (STE24 homolog, S. cerevisiae)
chr12_-_242255 0.467 NM_001190997
NM_016615
SLC6A13

solute carrier family 6 (neurotransmitter transporter, GABA), member 13

chr11_-_13474101 0.466 NM_000315
PTH
parathyroid hormone
chr6_-_132980901 0.464 NM_014626
TAAR2
trace amine associated receptor 2
chr14_-_69616616 0.462 NM_182936
NM_001130417
SLC8A3

solute carrier family 8 (sodium/calcium exchanger), member 3

chr17_+_39603599 0.460 NM_080863
ASB16
ankyrin repeat and SOCS box containing 16
chr13_-_45654327 0.455 NM_002298
LCP1
lymphocyte cytosolic protein 1 (L-plastin)
chr1_-_100416358 0.455 NM_144620
LRRC39
leucine rich repeat containing 39
chr5_+_140730014 0.454 NM_018924
NM_032097
PCDHGB3

protocadherin gamma subfamily B, 3

chr1_+_92405196 0.453 NM_015237
KIAA1107
KIAA1107
chr4_-_88669625 0.453 NM_001128310
NM_004684
SPARCL1

SPARC-like 1 (hevin)

chr9_+_5440455 0.451 NM_014143
CD274
CD274 molecule
chr3_+_36396948 0.450 NM_003149
STAC
SH3 and cysteine rich domain
chr5_-_176760242 0.448 NM_001029886
PFN3
profilin 3
chr3_+_120982020 0.442 NM_003889
NM_033013
NR1I2

nuclear receptor subfamily 1, group I, member 2

chr17_+_7125702 0.440 NM_001042
SLC2A4
solute carrier family 2 (facilitated glucose transporter), member 4
chrX_-_30237403 0.437 NM_000475
NR0B1
nuclear receptor subfamily 0, group B, member 1
chr2_-_215956429 0.433 FN1
fibronectin 1
chr1_+_158317967 0.430 NM_004983
KCNJ9
potassium inwardly-rectifying channel, subfamily J, member 9
chr22_-_49363711 0.429 NM_004377
NM_152246
NM_001145134
NM_001145135
NM_001145136
NM_152245
CPT1B





carnitine palmitoyltransferase 1B (muscle)





chr22_-_35545462 0.426 NM_002854
PVALB
parvalbumin
chr2_+_165860528 0.425 NM_001040143
SCN2A
sodium channel, voltage-gated, type II, alpha subunit
chr12_+_77781903 0.423 NM_001135805
SYT1
synaptotagmin I
chr8_-_17787342 0.422 FGL1
fibrinogen-like 1
chr1_-_151280201 0.421 NM_006945
SPRR2D
small proline-rich protein 2D
chr12_+_15590552 0.417 NM_030668
NM_030669
NM_030670
NM_030671
PTPRO



protein tyrosine phosphatase, receptor type, O



chr18_-_33399601 0.414 CELF4
CUGBP, Elav-like family member 4
chr14_-_30927931 0.413 NM_015473
HEATR5A
HEAT repeat containing 5A
chr10_-_115413630 0.411 NM_006175
NM_198060
NRAP

nebulin-related anchoring protein

chr11_+_128751044 0.411 NM_003658
BARX2
BARX homeobox 2
chr1_+_207944807 0.411 NM_005525
HSD11B1
hydroxysteroid (11-beta) dehydrogenase 1
chr7_-_83108682 0.409 NM_001178129
SEMA3E
sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3E
chr9_+_99303282 0.407 NM_001166116
TMOD1
tropomodulin 1
chr1_+_42773146 0.407 NM_001080850
CCDC30
coiled-coil domain containing 30
chr14_-_103058865 0.405 NM_001823
CKB
creatine kinase, brain
chr16_+_14187965 0.404 MKL2
MKL/myocardin-like 2
chr2_-_171796069 0.403 NM_001136554
TLK1
tousled-like kinase 1
chrX_-_15593074 0.402 NM_020665
TMEM27
transmembrane protein 27
chr11_+_60016826 0.402 NM_001164470
NM_017716
MS4A12

membrane-spanning 4-domains, subfamily A, member 12

chr21_+_14510336 0.402 NM_144770
RBM11
RNA binding motif protein 11
chr11_+_69176391 0.401 CCND1
cyclin D1
chr4_-_80548378 0.401 NM_033214
GK2
glycerol kinase 2
chr5_+_139485703 0.401 NM_001007189
C5orf53
chromosome 5 open reading frame 53
chr15_+_40438989 0.398 NM_000070
NM_024344
NM_173087
CAPN3


calpain 3, (p94)


chr1_-_151296611 0.395 NM_005988
SPRR2A
small proline-rich protein 2A
chr9_+_21430439 0.387 NM_024013
IFNA1
interferon, alpha 1
chr9_-_21375258 0.385 NM_000605
IFNA2
interferon, alpha 2
chr11_-_8921155 0.384 NM_020646
ASCL3
achaete-scute complex homolog 3 (Drosophila)
chr8_-_42353719 0.383 NM_014420
DKK4
dickkopf homolog 4 (Xenopus laevis)
chr5_+_140532385 0.382 NM_018940
PCDHB7
protocadherin beta 7
chrX_-_128485121 0.382 SMARCA1
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 1
chr4_+_111053488 0.380 NM_001178130
NM_001178131
NM_001963
EGF


epidermal growth factor


chr3_-_150993299 0.380 NM_001144960
C3orf16
chromosome 3 open reading frame 16
chr6_+_46822657 0.378 NM_001162435
LOC100287718
ankyrin repeat domain containing gene
chr7_+_128136347 0.376 FAM71F1
family with sequence similarity 71, member F1
chr16_-_31347151 0.376 NM_005205
COX6A2
cytochrome c oxidase subunit VIa polypeptide 2
chr12_+_105501161 0.373 NM_213594
RFX4
regulatory factor X, 4 (influences HLA class II expression)
chr17_+_41327449 0.370 NM_001123066
NM_001123067
NM_005910
NM_016834
NM_016835
NM_016841
MAPT





microtubule-associated protein tau





chr8_-_26780645 0.369


chr3_-_47909001 0.361 MAP4
microtubule-associated protein 4
chr3_+_171560104 0.361 NM_001145097
SKIL
SKI-like oncogene
chr2_-_18634257 0.361 NM_001002006
NM_033253
NT5C1B-RDH14
NT5C1B

NT5C1B-RDH14 readthrough
5'-nucleotidase, cytosolic IB

chr9_-_21156609 0.359 NM_002175
IFNA21
interferon, alpha 21
chrX_-_128485062 0.357 SMARCA1
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 1
chr12_+_53178834 0.355 NM_001184976
NCKAP1L
NCK-associated protein 1-like
chr22_+_40372957 0.354 XRCC6
X-ray repair complementing defective repair in Chinese hamster cells 6
chr7_-_15692551 0.353 MEOX2
mesenchyme homeobox 2
chr19_-_51856129 0.352 NM_145056
DACT3
dapper, antagonist of beta-catenin, homolog 3 (Xenopus laevis)
chr13_+_42046182 0.352 NM_003701
TNFSF11
tumor necrosis factor (ligand) superfamily, member 11
chr12_+_8866416 0.351 NM_144670
A2ML1
alpha-2-macroglobulin-like 1
chr13_-_45654292 0.351 LCP1
lymphocyte cytosolic protein 1 (L-plastin)
chr2_-_179623030 0.351 NM_173648
CCDC141
coiled-coil domain containing 141
chrX_-_128485134 0.350 NM_003069
NM_139035
SMARCA1

SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 1

chr8_+_104900591 0.349 NM_014677
RIMS2
regulating synaptic membrane exocytosis 2
chr8_-_26780665 0.347 ADRA1A
adrenergic, alpha-1A-, receptor
chr21_+_38550739 0.343 NM_170736
KCNJ15
potassium inwardly-rectifying channel, subfamily J, member 15
chr22_+_20899155 0.342


chr9_-_99740243 0.342 NM_197978
HEMGN
hemogen
chr1_-_181540631 0.339 NM_170706
NMNAT2
nicotinamide nucleotide adenylyltransferase 2
chr6_-_76259976 0.339 NM_015687
FILIP1
filamin A interacting protein 1
chr3_+_23904086 0.338 UBE2E1
ubiquitin-conjugating enzyme E2E 1 (UBC4/5 homolog, yeast)
chr1_-_155336223 0.338 NM_001004341
ETV3L
ets variant 3-like
chr6_-_130578110 0.338 NM_152552
SAMD3
sterile alpha motif domain containing 3
chr6_-_41811916 0.337 NM_001167827
TFEB
transcription factor EB
chr2_-_121964373 0.337 CLASP1
cytoplasmic linker associated protein 1
chr2_-_200038055 0.337 NM_001172517
SATB2
SATB homeobox 2
chr8_-_23768242 0.334 NM_003155
STC1
stanniocalcin 1
chr15_+_63156206 0.333 NM_001101362
KBTBD13
kelch repeat and BTB (POZ) domain containing 13
chr2_-_224574860 0.331 SERPINE2
serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2
chr7_-_130021845 0.331 NM_052933
TSGA13
testis specific, 13
chr4_-_187114407 0.330 SORBS2
sorbin and SH3 domain containing 2
chr10_-_75080784 0.330 NM_024875
SYNPO2L
synaptopodin 2-like
chr12_-_68291208 0.329 NM_201550
LRRC10
leucine rich repeat containing 10
chr15_-_48192804 0.328 ATP8B4
ATPase, class I, type 8B, member 4
chr15_+_38318528 0.326 PAK6
p21 protein (Cdc42/Rac)-activated kinase 6
chr2_+_161701711 0.326 NM_004180
NM_133484
TANK

TRAF family member-associated NFKB activator

chr17_-_70367479 0.325 NM_000835
GRIN2C
glutamate receptor, ionotropic, N-methyl D-aspartate 2C
chr19_+_17723285 0.324 NM_001161359
NM_015122
FCHO1

FCH domain only 1

chr3_-_150533948 0.324 NM_001184723
NM_138786
TM4SF18

transmembrane 4 L six family member 18

chr1_+_154478574 0.319 NM_199173
BGLAP
bone gamma-carboxyglutamate (gla) protein
chr9_-_21229975 0.318 NM_002172
IFNA14
interferon, alpha 14
chr2_+_204509698 0.314 NM_012092
ICOS
inducible T-cell co-stimulator
chr2_-_189752575 0.314 NM_000393
COL5A2
collagen, type V, alpha 2
chr19_-_55358091 0.314 NM_152358
IZUMO2
IZUMO family member 2
chr13_-_45654296 0.313 LCP1
lymphocyte cytosolic protein 1 (L-plastin)
chr13_-_97916768 0.313 STK24
serine/threonine kinase 24
chr2_+_69055208 0.312 NM_019617
GKN1
gastrokine 1
chr13_-_35327798 0.308 NM_001195415
NM_001195416
NM_001195430
DCLK1


doublecortin-like kinase 1


chr12_+_47205681 0.308 NM_001005203
OR8S1
olfactory receptor, family 8, subfamily S, member 1
chr3_-_46224791 0.307 NM_001295
CCR1
chemokine (C-C motif) receptor 1
chr1_-_148959945 0.305 NM_032132
HORMAD1
HORMA domain containing 1
chr12_-_10215942 0.304 NM_001172632
NM_001172633
NM_002543
OLR1


oxidized low density lipoprotein (lectin-like) receptor 1


chr21_-_18697829 0.303 NM_002772
TMPRSS15
transmembrane protease, serine 15
chr5_-_35974493 0.303 NM_001042625
NM_144647
CAPSL

calcyphosine-like

chr14_-_54977015 0.302 NM_199047
TBPL2
TATA box binding protein like 2
chr10_+_80743769 0.302 ZMIZ1
zinc finger, MIZ-type containing 1
chr21_-_41140908 0.301 NM_001389
DSCAM
Down syndrome cell adhesion molecule
chr3_-_125162707 0.301 CCDC14
coiled-coil domain containing 14
chr10_+_83627422 0.301 NM_001165973
NRG3
neuregulin 3
chr5_-_37220702 0.300 C5orf42
chromosome 5 open reading frame 42
chr15_+_38296920 0.300 NM_001128628
NM_001128629
PAK6

p21 protein (Cdc42/Rac)-activated kinase 6

chr7_+_99263571 0.300 NM_022820
NM_057095
NM_057096
CYP3A43


cytochrome P450, family 3, subfamily A, polypeptide 43


chr22_-_16060485 0.299 NM_177405
CECR1
cat eye syndrome chromosome region, candidate 1
chr6_+_152170146 0.298 NM_001122740
ESR1
estrogen receptor 1
chr4_+_37569093 0.295 NM_015173
TBC1D1
TBC1 (tre-2/USP6, BUB2, cdc16) domain family, member 1
chr3_+_188197029 0.291



Gene Ontology Analysis

Nothing significant found in process category.

Nothing significant found in compartment category.

Nothing significant found in function category.